Sunday, 18 August 2019

The Coconut Whisperers Sunday Movie: Johnny O'Clock


Johnny O'Clock is a 1947 film noir crime film written and directed by Robert Rossen, based on a story by Milton Holmes. The drama features Dick Powell, Evelyn Keyes, and Lee J. Cobb, with Jeff Chandler making his film debut in a small role.

Plot
Johnny O'Clock (Dick Powell) is a junior partner in a posh casino with Guido Marchettis (Thomas Gomez). Complicating their longtime working relationship is Guido's wife Nelle (Ellen Drew), who is still in love with former boyfriend Johnny. She gives Johnny an expensive custom pocket watch, the twin of a birthday present she gave her husband, except Johnny's has a romantic engraving on the back.
Johnny gives the watch, along with a rejection note, to Harriet Hobson (Nina Foch), a hat-check girl at the casino, to return to Nelle. Harriet, however, apparently commits suicide using gas. Her sister Nancy (Evelyn Keyes) shows up to find out what happened. She becomes attracted to Johnny. They eventually learn from Police Inspector Koch (Lee J. Cobb) that Harriet was killed by poison.
Harriet was dating Chuck Blayden (Jim Bannon), a crooked cop who is trying to persuade Guido to let him take Johnny's place. When Blayden also turns up dead, Koch suspects that either Johnny or Marchettis is responsible.
Though Johnny tries to resist, little by little, he falls for Nancy. When Koch shows both Johnny and Marchettis Johnny's watch and note, Johnny tells Nancy their relationship is through and takes her to the airport. As he is driving away, however, he narrowly survives a drive-by shooting, and Nancy realizes he was only trying to protect her. She refuses to leave him.
Johnny decides to flee to South America with Nancy, but not before brazenly cashing in his share of the casino. Marchettis pulls out a gun when Johnny's back is turned. They shoot it out; Marchettis is killed and Johnny wounded. Afterward, Nelle offers to testify it was self-defense, but only if he will come back to her. He refuses, so she tells Koch it was cold-blooded murder. Johnny's first instinct is to run away, but Nancy convinces him to give himself up.
Cast
Dick Powell as Johnny O'Clock
Evelyn Keyes as Nancy Hobson
Lee J. Cobb as Inspector Koch
Ellen Drew as Nelle Marchettis
Nina Foch as Harriet Hobson
Thomas Gomez as Guido Marchettis
John Kellogg as Charlie
Jim Bannon as Chuck Blayden
Mabel Paige as Slatternly Woman Tenant
Phil Brown as Phil, Hotel Clerk
Jeff Chandler as Turk
Read more on Wiki: https://en.wikipedia.org/wi...
For your viewing pleasure & comment the full 1 hour 35 minute movie.
Johnny O'Clock (1947) [Film Noir] 


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Why fecal transplants could be the next frontier in fighting skin cancer

Graham Slaughter, CTV News  Writer - Aug 16 , 2019
https://www.theloop.ca/ctvnews/why-fecal-transplants-could-be-the-next-frontier-in-fighting-skin-cancer/

A team of Canadian researchers is among the first in the world to test whether fecal transplants could help treat the deadliest form of skin cancer. 

 

 

A team of Canadian researchers is among the first in the world to test whether fecal transplants could help treat the deadliest form of skin cancer, melanoma.

Twenty patients with advanced stage disease are part of the phase one study out of the Lawson Health Research Institute in London, Ont. Participants have been prescribed pills filled with purified fecal bacteria, and they will then undergo immunotherapy in hopes of stimulating their bodies to kill cancer.

The hope is that transplanting healthy gut bacteria to cancer patients will boost their immune systems and make the immunotherapy drugs more effective. In turn, their bodies will be primed to destroy cancer cells.

The study is still in its early stages, but scientists have already seen promising signs the immune cells are revving up in the first two patients.

“We are getting some signs that the immune system is responding to these transplants,” said Dr. Michael Silverman, an associate scientist with the hospital. “We’re excited but we don’t want to give off the impression that this is a proven phenomenon yet, because it’s too early.”

Typically, immunotherapy with checkpoint inhibitors or PD-1 drugs is only successful in about half of patients. But preliminary research has shown that a person’s gut bacteria may play a role in whether their body responds to the treatment.

“Our hope is that every one of our patients will have a complete cure,” said Dr. John Lenehan, an associate scientist and oncologist with the hospital. “Although we’d be very happy if we had more than just 50 per cent responding to the treatment.”

Gut bacteria is having a bit of a moment in the medical world. Previous research has shown that the multitude of microorganisms in the human gut -- known among scientists as the microbiome -- have wider implications on a person’s overall health. Multiple sclerosis, inflammatory bowel disease and Alzheimer’s disease have all been linked to gut bacteria.

“Historically, the poop that comes out was felt to be either leftover food, or stuff that was not important, just bacteria that had no impact. Now we’re realizing that the organisms within the gut -- the gut microbiome -- are critically important in maintaining human health,” Silverman said.

Treating cancer with another person’s fecal matter may seem odd, and possibly even gross. But Emma Allen-Vercoe, a microbiologist at the University of Guelph, says the treatment doesn’t seem unusual to her. Instead, she calls it “a very smart strategy.”

“What I don’t think a lot of people realize is that the microbiome in the gut does an awful lot of talking to us … and so the idea that the microbiome might be used to help fine tune some of the treatments that we use to modulate the immune system and cancer treatment is not very far-fetched to people like me who understand the microbiome. But I think to the general public it comes as a bit of a shock,” she said.

Patients involved in the London study don’t seem fazed by the idea, either. Stool samples are gathered from healthy donors and undergo special treatment. The pills, which are taken orally, are tasteless and do not resemble human feces.
“If they have to swallow a bunch of pills they don’t seem that bothered by that. Even knowing that there’s stool inside, that’s fine with them. They want to live longer,” Lenehan said.

The study is the first of its kind in Canada to conduct full fecal transplants in cancer patients in hopes of boosting their responses to immunotherapy.
Research is expected to take two years. Doctors will monitor whether the gut bacteria is successful at repairing the immune system and helping shrink tumours.

If the method is effective, fecal transplants could be studied on a variety of cancers.

“We’re excited, we think it is a whole new field,” Silverman said.

A similar study is underway in Toronto. Researchers at Princess Margaret Hospital are using select microbes isolated from health donors and testing them on patients with several different kinds of solid tumours. The study is also in its early stages.

Allen-Vercoe, who is involved in the Toronto study, says research into the microbiome is a “very hot new area” of medicine that is gathering plenty of attention.

“I think it’s an area of such high excitement for the research community that I wouldn’t be surprised if this is going on quite widely around the world,” she said.

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Spicy Hash Browns For Breakfast
Easy breakfast recipe that you can make in 25 minutes
By Spice Bangla, Published on Mar 23, 2019 https://www.spicebangla.com...




These easy to make hash browns are perfect for breakfast. They are super delicious with a crispy exterior and fluffy center.
Prep Time 15 mins, Cook Time 10 mins, Total Time 25 mins, Serving: 5 pieces
Ingredients
3 Medium Size Potatoes
4 Tbsp All Purpose Flour
4 Tbsp Mozzarella Cheese Shredded
1 Large Egg
1 Small Onion Finely Chopped
1 Tsp Garlic Grated
1 Tbsp Coriander Freshly Chopped
1/2 Tsp Salt
1/2 Tsp Red Chili Powder/paprika Powder
1/4 Tsp Black Pepper
4 Tbsp Vegetable Oil For Frying.
Directions 
Shred potatoes using a vegetable grater. Rinse shredded potatoes with cold water until water is clear, then drain and squeeze dry. (rinsing shredded potatoes with cold water helps remove excess starch and make potatotes more crispy)
Place them in a bowl and add in the flour, cheese, egg, onion, garlic, coriander, salt, red chili powder, and black pepper powder. Then mix everything until combined.
In a large frying pan heat about 3-4 tbsp oil over medium heat. When oil is sizzling hot, place potatoes into the pan in a 1/2 inch thick layer and shape them in a rectangle or whatever shape you like. Cook each side for about 4 minutes or until golden brown. You can cook 2-3 in one batch or more if youre using a larger skillet.
Take them off the pan and place them on paper towels. Serve immediately with ketchup or any sauce of your choice. Enjoy!
For more directions watch this video

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Fredo: Icon for Our Times

Fredo: Icon for Our Times


NEW YORK, NEW YORK - MAY 15: Chris Cuomo of CNN’s Cuomo Prime Time speaks onstage during the WarnerMedia Upfront 2019 show at The Theater at Madison Square Garden on May 15, 2019 in New York City. 602140 (Photo by Dimitrios Kambouris/Getty Images for WarnerMedia)
Dimitrios Kambouris/Getty Images for WarnerMedia
9:07

Chris Cuomo may have only a middling show on CNN, but he seems destined to be an eternal “winner” in pop-culture mockery and notoriety. Cuomo’s outburst, revealed on August 12, was a little bit newsworthy for its threatened violence; the CNN anchor told another man who had accosted him, “You’re going to have a problem . . . I’ll [bleeping] ruin your [bleep]. I’ll [bleeping] throw you down these stairs.” 

Okay, so plenty of people in public life lose their cool in the midst of random confrontations. And no doubt there will be another such incident, somewhere, tomorrow.   
Yet what made Cuomo really stand out was his embrace of a particular movie reference, one that hits the funny bone of popular culture. That is, Cuomo got unglued by the comparison of himself as “Fredo,” one of the fictional Corleone brothers in the Godfathermovies of 1972 and 1974. To hit the point harder, Fredo was the incompetent, jealous, and, ultimately, treacherous brother. As the character says, helplessly and dishonestly, in the second Godfather film, “I can handle things, I’m smart! Not like everybody says.” 
So if we turn from reel life to real life, we can see that Breitbart News’s John Nolte has been gleeful in slapping the “Fredo” label on Cuomo. And obviously, the comparison has gotten under Cuomo’s skin; hence on that video, he is seen yelling at a stranger, as if the volume of his voice will refute the Cuomo = Fredo analogy: 
No punk-ass bitches on the right call me Fredo. My name is Chris Cuomo. I’m an anchor on CNN. Fredo is from The Godfather. He was the weak brother.
Defensive, much? As Ronald Reagan, who knew a thing or two about both movies and public life, liked to say, “If you’re explaining, you’re losing.” In other words, in the battle to separate himself from the Fredo trope, Cuomo simply defeated himself.
From a PR perspective, Cuomo dug himself even deeper when he tried to argue that “Fredo” was a slur against Italian-Americans, akin to the “n-word.”  That reach of a defense drew heavy fire from Trevor Noah, the African-born host of Comedy Central’s Daily Show. Moreover, other wiseguys pointed out that “Fredo” has been thrown around a lot on CNN, even on Cuomo’s own show—and the host hadn’t objected to this supposed mortal insult. Indeed, Cuomo has even used the reference on himself. 
Powered by such delicious hypocrisy, the Cuomo-Fredo meme took on more prominence, aided by butt-kicking tweets from Donald Trump Jr. and Donald Trump Sr. As the President said, “I thought Chris was Fredo also. The truth hurts. Totally lost it! Low ratings.” (The Trump campaign is now even selling a “Fredo Unhinged” tee shirt.)   
On August 13, “Fredo” was the number one “Trending in USA” topic on Twitter. 
And the following day, the New York Post piled on with a cover, “The Godbother: Chris Cuomo Fury at ‘Fredo’ Insult,” showing a doctored photo of Chris Cuomo, his late father Mario, and his brother Andrew. Mario and Andrew, we might note, were both elected multiple times to the governorship of the Empire State, whereas Chris has his . . . TV show. 
In the snarkily triumphant tweet of conservative activist Candace Owens, “I am warmed by the fact that @ChrisCuomo will be known as Fredo in perpetuity.”
Yet beyond the catastrophic optics of Cuomo’s rant, joined by damage-control that did more damage, there’s the interesting question of how it was that the Godfather movies gained so much prominence in our culture, such that so many people would pick up instantly on the Fredo reference.
The Godfather
Marlon Brando, Al Pacino, James Caan, and John Cazale (IMDB).
Back in 1972, The Godfather was a massive hit; the gangster epic was nominated for 11 Oscars and won three—for best picture, for best actor (Marlon Brando), and best adapted screenplay. Even in that pre-Internet era, memes from the film flowed fast and furious; for instance, the phrase, “Make him an offer he can’t refuse,” became a common quip, said with humor, or menace—or both.  Not coincidentally, the Godfather’s Pizza chain was founded in 1973. 
Marlon Brando receives a message in a scene from the film 'The Godfather', 1972. (Photo by Paramount/Getty Images)
Marlon Brando receives a message in a scene from The Godfather. (Paramount/Getty Images)
Then, in 1974, along came The Godfather: Part II. It was also nominated for 11 Oscars and won six, including, again, best picture and best adapted screenplay.
1974, American actor John Cazale (left) (1936 - 1978) puts his hand on the arm of American actor Al Pacino in a still from director Francis Ford Coppola's film, 'The Godfather; Part II,' based on the novel by Mario Puzo. (Photo by Paramount Pictures/Getty Images)
John Cazale (left) puts his hand on the arm of Al Pacino in a still from Director Francis Ford Coppola’s The Godfather; Part II. (Paramount Pictures/Getty Images)
Thus the drama of the Corleones had become central to the pop-culture canon; Godfatherreferences and quotes have since abounded, not only around barstools and poker tables, but even at the highest levels of corporate America.
Moreover, Roger Stone, the one-time Trump associate who delighted in sporting gangster-ish suits, made reference to the second film when he suggested to a possible Russia-story witness that he consider Frank Pentangeli, a character who refuses to testify against the mob.
So today, one can go to IMDB.com, find the section on movie quotes—all of them posted by admiring fans—and read practically the entire script of both movies.  That’s how popular the films are.  (We might note that there was a 1990 sequel, The Godfather: Part III; it was a modest financial success, but an enormous critical failure and cultural disappointment.   And so Godfather fans, protective of their treasured cinematic “turf,” generally pretend it doesn’t exist.)  
Today, the first two films are so integral to our thinking that they can even be said, in large part, to occupy the psychic space once held by The Iliad and The Odyssey, the classic works of the ancient Greek poet Homer, who is generally seen as the father of Western literature.  
In earlier eras, educated people were conversant with the mythical characters from those two epics, including Odysseus, Achilles, and Helen of Troy.  Indeed, dutiful students could also how to interpret references to Circe and her sirens, Polyphemus the cyclops, and to Penelope and her suitors.  
Yet times change, and people don’t read as much as they once did. But they do watch movies. And so, for better or worse, most people today know more about Vito Corleone, Michael Corleone—and, yes, of course, Fredo Corleone—than about any old Greek protagonist. Folks are more likely to get references to “go to the mattresses” or “leave the gun, take the cannoli” than to such Homeric phrases as “rosy-fingered dawn” and “wine-dark sea.” 
Still, for all this change, we can pause to consider that in some ways, not much has changed.  That is, there’s perpetual fascination with heroes, great deeds—and, yes, evil deeds. 
So while the differences across the millennia are enormous, similarities emerge. Achilles died for honor, and so, too, did Sonny Corleone.   Indeed, for the last century, since the 1931 film Scarface, movie audiences have thrilled to the operatic lives, and deaths, of mobsters. 
In an influential 1948 essay, “The Gangster as Tragic Hero,” Robert Warshow wrote of the gangster genre: “From its beginnings, it has been a consistent and astonishingly complete presentation of the modern sense of tragedy.”  And who doesn’t love a sad story, especially if it involves rising to the heights, before sinking to the depths? 
Continuing, Warshow added, “In ways that we do not easily or willingly define, the gangster speaks for us, expressing that part of the American psyche which rejects the qualities and the demands of American life.”  So we can see that gangsterism, in its lethal immediacy, takes us back, in a fashion, to primal combats—even to, as Homer put it, “the windy plains of Troy.” 
And yet gangsterism is more than just carnage; it’s also a style of operating. Gangsters might spend much of their lives in violence, and yet at the same time, they are also conspirators—and conspiracy theories, too, are endlessly popular. That’s why, long before the Godfather movies, leaving aside outright criminal gangs, people spoke of “mafias,” referring to organized groups that may, or may not, be skirting the law—a Kennedy Mafia, a Lavender Mafia, and so on.  
As for the Godfather movies of the ’70s, they landed in the wake of Vietnam and Watergate, at a time of rising mistrust of authority, as well as of official explanations. Thus when the films offered a sinister interpretation of such historical topics as the revival of Frank Sinatra’s career in the early ’50s, or the rise of Nevada gambling in that same decade, audiences were primed to pay heed.   
So now today, nearly a half-century later, are Americans any more trusting? Are they any more likely to take the word of those in power? As we consider the stinky Jeffrey Epstein case, or the equally stinky case of Harvey Weinstein, or the smell still emanating from the Russia investigation, or from the Catholic Church—should we bestow our trust and confidence in any powerful person? Or in any large institution?    
Instead, perhaps, as we navigate these moral swamps, maybe we end up believing that it helps to have some cynical, even conspiratorial, wisdom of our own. After all, nobody wants to be a sucker, or to look like a chump. And so, for inspiration, we might cling to the street-wise wisdom of, say, Tom Hagen, the Corleone consigliere.
American actor Marlon Brando (1924 - 2004), in character as mob kingpin Don Vito Corleone, gestures as he sits at a table as colleague and compatriot Robert Duvall, as Tommy Hagen, sits behind him in a scene from the gangster film 'The Godfather,' directed by Francis Ford Coppola, 1972. (Photo by Paramount Studios courtesy of Getty Images)
Marlon Brando as Don Vito Corleone, gestures as he sits at a table as colleague and compatriot Robert Duvall, as Tommy Hagen, sits behind him in a scene from The Godfather. (Paramount Studios/Getty Images)
In the films, Tom was always so calm and cool, as well as observing and knowing. So when he whispered in the Don’s ear, as he did so often, we knew he had something sage to say–explaining how things really worked.
So in 2019, even after so much has changed, the Godfather movies are still vital, serving as cynical guides for a cynical age. Yes, they speak to us, with dark wisdom, in this very dark epoch.   

Russia Testing Nuclear-Powered Mega-Torpedo Near Where Deadly Explosion Occurred

Details are still emerging of the explosion of a nuclear-powered engine that killed at least seven people in northern Russia last week. Conflicting reports, rumors and speculation center around whether the engine was for a nuclear-powered cruise missile, codenamed Skyfall by NATO, or some other weapon-related reactor. One of the possible weapons in the frame is the Poseidon mega-torpedo. This new weapon is described as an Intercontinental Nuclear-Powered Nuclear-Armed Autonomous Torpedo by the U.S. government.
The unique drone-like weapon is in an entirely new category. Launched from a large submarine, potentially from under the protection of the arctic ice cap, it would have virtually unlimited range and Russia claims that it will run so deep that it cannot realistically be countered with existing weapons. It's designed to be armed with a nuclear warhead, reportedly of 2 megatons, which represents a slow but unstoppable death-knell for the residents of coastal cities such as New York or San Francisco in the event of a nuclear war. The Russian Ministry of Defense also claims that it will be usable against high value maritime targets such as the U.S. Navy's carrier battle groups.
It is massive, around 30 times larger than the heavyweight torpedoes commonly used aboard submarines, and twice as large as submarine launched ballistic missiles (SLBMs). Specially constructed submarines will be able to carry six Poseidon each. Unlike existing missile submarines, which are termed SSBNs, this type of submarine doesn't even have a designation yet. Possibly SSDN will be used to denote a nuclear powered drone-carrying submarine.
Poseidon is being tested in the region, my analysis of information gathered from public sources shows. For trials it is being launched by a special submarine based in Severodvinsk, near the Nyonoksa testing site where the explosion occurred. The submarine is named Sarov after the city where the All-Russian Scientific Research Institute of Experimental Physics, which developed the nuclear engine involved in the explosion, is based. Sarov is also the city where the victims of the blast were laid to rest. In recent years the Russian Ministry of Defense has been open about Sarov's role in the tests. The submarine rarely puts to sea but my analysis of information gathered from public sources shows that it did venture out into the White Sea in June, pointing to possible recent test launches.
Poseidon was first revealed to the public in dramatic fashion by Russian state media in the fall of 2015, when a slide on the new weapon was visible during a meeting with President Putin. The apparent security lapse was probably not by accident.
The project itself has since been traced back much further to the end of the Cold War, and defense watchers had an inkling of a giant torpedo-like weapon under development for about five years prior to the staged leak.
The weapon has been in testing since around 2014 and is likely to be nearing the production phase with deployments at sea from the early 2020s. The first submarine slated to carry the weapon operationally was launched in April in Severodvinsk. The gigantic Belgorod submarine is still undergoing fitting out and will not be operational for a few years. The second submarine, Khabarovsk, is also nearing completion and two more SSDNs are expected to follow, providing Russia with a new dimension in nuclear deterrence.

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